15TH SLS ANNUAL MEETING AND ENDO EXPO 2006 SCIENTIFIC ABSTRACTS
Supplement to
JSLS, JOURNAL OF THE SOCIETY OF LAPAROENDOSCOPIC SURGEONS
VOLUME 10, NUMBER 3
6101 General Surgery
Laparoscopic Fundoplication: the Beneficial Effects of Preservation of Short Gastric Vessels
M. Z. Aslam, MBBS, D. Garkuwa, FRCS, S. Johnson, MRCS, R. Rajagopal, FRCS, K. S. Wynne, FRCS
South Shields General Hospital
Introduction: In the operative treatment of gastroesophageal reflux disease, division or preservation of short gastric vessels has always remained a subject of controversy. This randomized study was performed to determine whether the preservation of short gastric vessels during laparoscopic fundoplication achieves an acceptably low incidence of postoperative complications while at the same time providing adequate control of reflux, and conferring long-term clinical benefit to the patient.
Methods: From January 2000 to January 2003, 73 patients (M: 36, F: 37; mean age, 44 years) with proven gastroesophageal reflux disease underwent laparoscopic fundoplication with preservation of short gastric vessels. Patients with esophageal motility disorder, with concurrent abdominal surgery or with a previous reflux surgery were excluded from the study. Clinical assessment was performed using a standardized clinical grading system to assess dysphagia, heartburn, bloating, and epigastric pain at 1, 6, and 12 months postoperatively.
Results: Average operating time was 45 minutes to 60 minutes, no open conversion was needed, and the average hospital stay was 36 hours. Postoperatively, the incidence of heartburn was 7% (5 patients) at 1 month and 1 year. The incidence of postoperative dysphagia and gas bloating was 27% (20) and 10% (7), respectively, at 1 month, which dropped down to 7% (5) and 1.4% (1), respectively, at 1 year. The overall patient satisfaction rate was 90% (65).
Conclusion: Preservation of short gastric vessels brings good results without an increase in dysphagia. The added benefits are reduced bloating, operating time, morbidity, and consequently hospital stay.
6102 Gynecology
Pathophysiology of Peritoneal Tissue Acidosis During Laparoscopic Surgery
O. A. Mynbaev, L. Dollé, S. Pismensky, C. A. Jacobi, B. Vanacker, M. Bracke
VUB, Belgium
Introduction: Parietal peritoneum (PP) acidosis during laparoscopy is a well-established phenomenon and a poorly understood mechanism. Our aim was to study the mechanism of PP acidosis during CO2 pneumoperitoneum.
Methods: “Because venous CO2 tension is considered representative of tissue PCO2.,” we monitored arterial and venous blood gas and acid-base and metabolite-lactate parameters during CO2 pneumoperitoneum in 10 anesthetized-ventilated rabbits (AVR) with increasing intraperitoneal pressure (IPP: 0, 5, 10, 15mm Hg) every 15 minutes. Blood flow was monitored in the abdominal aorta in 5 animals and in the inferior vena cava in another 5. Baseline parameters were obtained from 6 AVR.
Results: We found high pronounced PvCO2 and PaCO2 with corresponding decreased pH and increased lactate concentrations in both venous and arterial blood. Overall acid-base parameter changes were related to CO2 accumulation. Abdominal aorta and inferior vena cava blood flow were significantly affected.
Conclusions: The suggested mechanism of PP tissue acidosis during CO2 pneumoperitoneum is the considerably high mesothelial surface CO2 tension with subsequent CO2 saturation underlying PP tissue due to continuous CO2 insufflation. CO2 passes through PP and accumulates in venous and arterial blood due to increased tissue-to-venous and venous-to-arterial CO2 tension differences. PP acidosis severity directly depends on CO2 insufflation and its absorption, whereas the severity of blood gas and blood flow disturbances is related to the degree of IPP. Increased lactate concentrations and high tissue acidosis in hypoxic PP tissue can be the suitable microenvironment for rapid invasion and metastasis of transplanted cancer cells into the basal membrane after removing malignant tumors from the abdominal cavity via laparoscopy.
6103 Gynecology
Congenital Diaphragmatic Falciform Ligament Herniation: A Rare Case
D. G. Kolder, MD, W. S. Eubanks, MD
University of Missouri Hospitals and Clinics
The occurrence of diaphragmatic herniation involving only the falciform ligament is rare. In the era of minimally invasive surgery, herniation through the falciform ligament from multiple causes has been described. Several types of congenital and acquired hernias of the diaphragm have been well-defined. Anterior congenital hernias of the diaphragm (hernia of Morgagni) are rare and when detected, rarely contain liver or the falciform ligament. We present an unusual case of congenital herniation of the diaphragm containing the falciform ligament. The asymptomatic finding was discovered at laparoscopy, a finding not yet described in the literature.
6104 General Surgery
Randomized Clinical Trial of Three-Port Versus Standard Four-Port Laparoscopic Cholecystectomy
Manoj Kumar, MD, Akshay Pratap, MD, C. S. Agrawal, MD
B. P. Koirala Institute of Health Sciences, Dharan, Nepal
Introduction: Laparoscopic cholecystectomy (LC) for gallstone disease is widely accepted as a standard procedure performed using 4 trocars. The fourth (lateral) trocar is used to grasp the fundus of the gallbladder so as to expose Calot's triangle. It has been argued that the fourth trocar may not be necessary in most cases and that LC can be done safely with only 3 ports. The aim of this study was to investigate the technical feasibility, safety, and benefit of 3-port laparoscopic cholecystectomy versus standard 4-port laparoscopic cholecystectomy in our set up.
Methods: Between September 2004 and January 2005, 70 consecutive patients undergoing elective laparoscopic cholecystectomy for gallstone disease were randomized to be treated via either the 3-port or 4-port technique. Postoperative pain was assessed by using a 10-cm unscaled visual analogue score at the first, sixth, twelfth, and twenty-fourth hours after surgery.
Results: Demographic data were comparable in both groups. No difference was noted in the 2 groups regarding age, sex, weight, and ethnicity. In terms of outcome, no difference existed in success rate, quantity of oral analgesic (diclofenac sodium) requirement, or postoperative hospital stay. Overall pain score and patient satisfaction score were slightly better in the 3-port group. Patients in the 3-port group had shorter mean operative time (42.4 min vs. 64.3 min) than the 4-port group had.
Conclusion: The 3-port technique is as safe as the standard 4-port technique. The main advantages of the 3-port technique are that it causes less pain, is less expensive, and leaves fewer scars.
6106 General Surgery
Histology Examination of the Gallbladder in the Laparoscopic Era: Is it Justified?
Sajid Mahmud, MD, Il Alam, I. Alhamdani
Morriston Hospital, Swansea
Introduction: Gallbladder carcinoma (GBCa) is a rare malignancy that has a very poor prognosis. Laparoscopic cholecystectomy (LC) is the gold standard treatment for symptomatic gallstones. The aim of our study was to assess the incidence of GBCa and the possibility of reducing the routine histological examination of gallbladder specimens.
Method: Pathology laboratory data of gallbladder specimens over a 5-year period (June 2000 through July 2005) were analyzed retrospectively. The case notes were retrieved in all cases of malignancies.
Results: This study comprised 1452 specimen. Four (0.27%) cases of primary GBCa, 1 of primary B-cell lymphoma, 1 of secondary carcinoma, and 1 of intraepithelial neoplasia were detected. Operative notes revealed that a high index existed of suspicion of malignancy in all cases. Of the 4 primary GBCa, 3 were stage T2 and 1 was T4. Preoperative ultrasound suspected carcinoma in only 1 case but a thickened gallbladder wall was noted in all cases.
Conclusion: All cases of GBCa were suspected preoperatively or intraoperatively. Histological examination did not alter the management or outcome in any of the cases. We suggest that selectively sending specimens for histopathological examination would result in reduced demands on the histopathology department without compromising patient safety.
6107 General Surgery
Videothoracoscopic Neurophrenicotomy
Igor Polianskyi, Prof Dr Med, Yaroslav Dupeshko, MD, Vyacheslav Sakhatskyy, MD
Bukovinian State Medical Academy Chernivtsy
Introduction: Videolaparoscopic neurophrenicotomy is used to perform denervation of the diaphragm. The operation is indicated where denervation of the diaphragm is necessary to liquidate the residual cavity after pulmonectomy in cases of involuntary contractions of the diaphragm and in other cases. Morphological studies carried out on adult corpses revealed that phrenic nerves are situated on the surface of the pericardium and associated intimately with a. pericardiacophrenica and v. pericardiacophrenica. This structure reaches the diaphragm through the pericardiophrenicum positioning itself between the ligament’s leaves.
Methods: Based on the discovered patterns of topographic interrelations, we propose a small invasive neurophrenicotomy technique. With the patient in the supine position, the first trocar is inserted into the pleural cavity through the VII to VIII intercoastal spaces on the midauxiliary line. Through this port, a video camera is inserted. The lungs are collapsed by carbon dioxide insufflation. The second trocar is inserted through the IV intercoastal space on the anterior auxiliary line. The pericardiophrenicum ligament is mobilized between the pericardium and diaphragm by using the dissector. The ligament is cut between 2 applied clips. Relaxation of the diaphragm and the absence of its contraction after irritation of the phrenic nerve distal to the severance of the ligament can be used to prove adequate dissection of the phrenic nerve.
Results: The operation ended with pleural cavity drainage through one of the trocars.
Conclusion: The method proposed has been used in the clinical setting with favorable results.
6108 Urology
Conversion from Open to Robotic-Assisted Radical Prostatectomy Is Associated with a Reduction in Positive Surgical Margins Among Private Practice-Based Urologists
Ralph Madeb, Dragan Golijanin, Craig Nicholson, Joy Knopf, Kelly Picone, Frederick Tonetti, John R. Valvo, Louis Eichel
Center of Urology and University of Rochester School of Medicine, Rochester, New York
Introduction: Several recent studies have suggested that leaders in robotic surgery have decreased their own positive margin rates by switching from open to robot-assisted radical prostatectomy. Theoretically, this improvement is largely attributed to enhanced visualization of the deep pelvis and precision of dissection afforded by the instrumentation. To date, it has not been determined whether this phenomenon exists among nonfellowship-trained urologists in private practice. Herein, we describe the positive margin rates of 2 nonfellowship-trained private practice urologists who converted from open radical retropubic prostatectomy to robot-assisted laparoscopic radical prostatectomy.
Methods: The margin positivity data from 2 nonfellowship-trained, private practice urologists (surgeon 1 and surgeon 2) were reviewed retrospectively. The last 50 cases of open radical retropubic prostatectomy from each surgeon were compared with the first 50 and 43 robotic prostatectomy cases of surgeons 1 and 2, respectively. A positive surgical margin was defined as a tumor present at the inked margin of the prostate.
Results: A significant decrease occurred in the overall and pT2 positive margin rates for both surgeons. The overall positive margin rate and pT2 positive margin rate for surgeon 1 dropped from 44% to 20% and from 37% to 5.7%, respectively, after changing from open to robotic prostatectomy. For surgeon 2, the overall positive margin rate changed from 26% to 16% and the pT2 positive margin rate changed from 27.5% to 8% after converting.
Conclusion: Changing from open to robotic-assisted radical prostatectomy may improve the ability of urologists to obtain negative surgical margins. This phenomenon does seem to apply to nonfellowship-trained urologists in private practice and can be realized within the first 50 cases performed.
6109 General Surgery
Role of Subfascial Endoscopic Perforator Surgery (SEPS) by Harmonic Scalpel in the Management of Chronic Venous Insufficiency of the Lower Limbs
P. N. Agarwal, Ravi Kant, Sudhir K. Jain
Maulana Azad Medical College, University of New Delhi, New Delhi, India
Introduction: Thirty patients suffering from chronic venous insufficiency of the lower limbs were selected for this study. Disease in all patients was classified as class 3 through class 5 according to CEAPS classification. Ten patients had only skin changes, 8 had skin changes plus healed venous ulcers, and 12 had active venous ulcers.
Methods: Color Doppler was used in all patients to evaluate the venous system of both lower limbs to look for perforators and incompetence of the sapheno-femoral of sapheno-popliteal junction. All patients underwent subfascial endoscopic perforator surgery (SEPS) with the 2-port technique. A Harmonic scalpel was used to manage the perforators. SEPS was combined with flush ligation of sapheno-femoral junction and stripping of the long saphenous vein up to the knee joint. Patients were followed up in the surgical clinic on a monthly basis for 12 months. At 1-month follow-up, a repeat color Doppler study of the lower limb veins was performed to look for any residual perforators. In the follow-up, patients were monitored for healing of ulcers and reversal of skin changes. A note was also made of cosmetic outcome and return to activity.
Results: Ulcers have healed in all the patients, cosmetic results were good, and return to normal activity was early. No patient has experienced a recurrence. One patient developed wound infection and was managed with appropriate antibiotics. Early discharge of patients from the hospital was possible in all cases.
Conclusion: Our results are very encouraging. SEPS as a procedure of choice for the management of chronic venous disease of the lower limbs may have an appropriate role in the surgeon’s armamentarium.
6110 General Surgery
Combined Surgical and Endoscopic Rescue of Severe Sepsis After Bariatric Surgery
Gianluca Bonanomi, MD, Mario Traina, MD, Ilaria Tarantino, MD, Simona Di Caro, MD, Bruno Gridelli, MD
Minimally Invasive and Bariatric Surgery Program, Istituto Mediterraneo Trapianti e Terapie ad Alta Specializzazione, Palermo, Italy
Introduction: Gastric fistula is a serious complication of vertical banded gastroplasty. Failure to control the leakage and development of sepsis can lead to prolonged hospitalization and mortality.
Methods: A 32-year-old morbidly obese male was transferred to our intensive care unit with a clinical picture of severe sepsis following open vertical banded gastroplasty that was performed at another institution. The patient underwent 2 surgical attempts at fistula closure that were unsuccessful. On admission, the patient was critically ill, mechanically ventilated through a tracheostomy, and the abdominal laparotomy was completely dehiscent.
Results: Emergent abdominal CT scan with gastrographin showed the presence of high output gastric fistula at the angle of His and diffuse peritoneal collection. The patient underwent combined surgical placement of peritoneal drains and intraoperative endoscopic injection of cyanoacrylate glue and placement of a self-expanding covered stent over the fistula. The patient recovered from sepsis and was discharged home in fair clinical condition. At 1-year follow-up, the patient was stable, and an upper endoscopy was negative for stenosis or ulceration.
Conclusion: Combined surgical and endoscopic management of high output leakage following vertical banded gastroplasty may be a successful option to rescue patients with life-threatening sepsis.
6112 General Surgery
Role of Diagnostic Laparoscopy in Penetrating Abdominal Stab Wounds
Albeir Mousa, MD
Brookdale University Hospital and Medical Center
Introduction: The role of diagnostic laparoscopy (DL) in abdominal stab wounds (ASW) is not well characterized. This study was to define the role of DL in minimizing the number of exploratory laparotomies (EL).
Methods: Our trauma registry and operative log were used to identify patients with penetrating stab wound injuries to the anterior abdominal wall, who underwent laparoscopy with or without laparotomy during the past 36 months. Patient demographics, operative findings, complications, and length of stay were reviewed. The number of laparoscopic explorations, and therapeutic, nontherapeutic, and negative laparotomies were analyzed.
Results: There were 66 DL performed for ASW. Among those, only 37 were converted to EL. Peritoneal violations (PV) were present in 41 patients, and 30 of 37 (81%) EL were therapeutic laparotomies (TL). By using DL, 25 (38%) EL were prevented. Four patients had peritoneal violations on DL but did not undergo exploratory laparotomy. Seven of the 37 (19%) patients who underwent initial EL had a nontherapeutic laparotomy (NTL). All patients who underwent only DL were discharged within 36 hours, while patients who had NTL were discharged within 72 hours. No mortality and morbidity occurred within the DL group. Mean follow-up was 13 months, and no associated complications were encountered during this time.
Conclusions: Laparoscopy has an important diagnostic role in stable patients with penetrating abdominal trauma. It minimizes the number of negative exploratory laparotomies performed. In carefully selected patients, therapeutic laparoscopy is practical, feasible, and offers all the advantages of minimally invasive surgery. Evidence of PV is a reasonable indicator to determine the need for exploratory laparotomy and reduce nontherapeutic laparotomy.
6113 Gynecology
Embryoscopy in Recurrent Pregnancy Loss
H. J. A. Carp, MB, BS, FRCOG
Department of Obstetrics & Gynecology; Sheba Medical Center, Tel Hashomer, Tel Aviv University, Israel
Recurrent miscarriage can be due to maternal or embryonic causes. Maternal causes have been widely researched, but the treatment of maternal causes has been confounded by abnormal embryos that have not been diagnosed. Fetal causes of pregnancy loss include structural anomalies that are incompatible with life and chromosomal aberrations. The diagnosis of both of these is problematic at present. Eighty-nine percent of recurrent miscarriages occur in the first trimester, when the embryo is too small to be diagnosed as normal or abnormal on ultrasound. Phillip and Kalousek have reported that 31% of missed abortions are "disorganized," ie, structurally abnormal on embryoscopy. Embryonic karyotyping is problematic due to the overgrowth of maternal tissue, infection of the preparation, and culture failure. Ferro et al have used embryoscopy to take a directed sample from the embryo, thereby avoiding contamination by maternal tissue. A pilot study on embryoscopy is being carried out at the Sheba Medical Center to accurately diagnose structural anomalies (disorganized embryos) and to take an accurate biopsy of embryonic tissue for karyotyping. After confirmation of a missed abortion by ultrasound, embryoscopy is performed with the patient under general anesthesia during dilatation and curettage. The embryo is visualized, the findings are recorded, and biopsies are taken from the embryo and placental villi for genetic analysis. The importance of accurate diagnosis in recurrent miscarriage cannot be overstressed. Until now, the various treatments for maternal causes of pregnancy loss (immunotherapy, thromboprophylaxis, hormone support, and others) and for fetal causes (PGD) have been assessed on an empirical basis. Embryoscopy allows these treatment modalities to be assessed rationally in an evidence-based approach when an accurate diagnosis of cause is available.
6114 General Surgery
Laparoscopic Retrieval of a Large Retained Fecalith after Laparoscopic Appendectomy
Bryan S. Helsel, MD, Christopher H. Moon, MD, Richard K. Inae, MD, Ian H. Freeman, MD
Department of Surgery, Tripler Army Medical Center, Tripler, Hawaii
Introduction: Retained fecaliths after an appendectomy is a rare event. Due to the associated high rate of abscess formation, most authorities recommend removal. Difficulty locating a lost fecalith may necessitate open conversion of a laparoscopic procedure.
Methods: We report the case of a 25-year-old male who underwent laparoscopic appendectomy for a gangrenous, perforated appendix. He was found to have a large fecalith, 12x10mm in size. During the procedure, it was lost. Despite a detailed and careful exploration, we were unable to find and extract the fecalith. Postoperatively, the patient developed an ileus. Radiographic studies were performed of adjacent tissue. On postoperative day 4, an exploratory laparoscopy was performed. Trocars were inserted to localize the fecalith, which included a 10-mm infraumbilical port, a 5-mm left lower quadrant port, and a 5-mm right lower quadrant port. This showed it to be in the pelvis with an associated thickened site. Using the radiographic studies as a guide, the fecalith was located and extracted with endograspers and an endocatch bag.
Results: The patient subsequently improved and was discharged 5 days later without further incident.
Conclusion: We conclude that laparoscopic retrieval following radiographic localization of a retained fecalith is a viable alternative to immediate open conversion.The views expressed in this abstract are those of the authors and do not reflect the official policy or position of the Department of the Army, Department of Defense, or the US Government.
6115 General Surgery
Laparoscopic Versus Open Appendectomy in Perforated Appendicitis
Fukami Yasuyuki, MD, Hasegawa Hiroshi, MD, Sakamoto Eiji, MD,Komatsu Shunichiro, MD,
Hiromaysu Takashi, MD
Department of Surgery, Nagoya Daini Red Cross Hospital, Nagoya, Japan
Introduction: The purpose of this clinical study was to evaluate the efficacy of
laparoscopic appendectomy in patients with perforated appendicitis.
Methods: Between January 1999 and December 2004, 73 consecutive patients underwent appendectomy for perforated appendicitis. Thirty-nine underwent open appendectomy (OA) during the first 3 years (between January 1999 and December 2001), 34 underwent laparoscopic appendectomy (LA) during the last 3 years (between January 2002 and December 2004). Laparoscopic appendectomy was performed using a 3-trocar technique and the endoscopic stapler.
Results: No case needed to be converted to OA from LA. No statistically significant difference in the operative time in minutes was found between the LA (97.9±30.6) and OA (92.0±31.4). LA required less analgesic useÅ@(LA, 2.7 times; OA, 8.3 times; P<0.001), and oral intake was resumed earlier (LA, 2.6 days; OA, 5.1 days; P<0.05). Postoperative stay was shorter in LA (LA, 11.7 days; OA, 25.8 days; P<0.001). Postoperative wound infection was less frequent in LA (LA, 8.8%; OA, 43.6%; P=0.0022).
Conclusions: Laparoscopic appendectomy for perforated appendicitis has significant advantages over open appendectomy with respect to frequency of analgesic use, start of oral feeding, postoperative stay, and postoperative wound infection.
6115 General Surgery
Laparoscopic Versus Open Appendectomy in Perforated Appendicitis
Fukami Yasuyuki, MD, Hasegawa Hiroshi, MD, Sakamoto Eiji, MD,
Komatsu Shunichiro, MD, Hiromaysu Takashi, MD
Department of Surgery, Nagoya Daini Red Cross Hospital, Nagoya, Japan
Introduction: The purpose of this clinical study was to evaluate the efficacy of
laparoscopic appendectomy in patients with perforated appendicitis.
Methods: Between January 1999 and December 2004, 73 consecutive patients underwent appendectomy for perforated appendicitis. Thirty-nine underwent open appendectomy (OA) during the first 3 years (between January 1999 and December 2001), 34 underwent laparoscopic appendectomy (LA) during the last 3 years (between January 2002 and December 2004). Laparoscopic appendectomy was performed using a 3-trocar technique and the endoscopic stapler.
Results: No case needed to be converted to OA from LA. No statistically significant difference in the operative time in minutes was found between the LA (97.9±30.6) and OA (92.0±31.4). LA required less analgesic useÅ@(LA, 2.7 times; OA, 8.3 times; P<0.001), and oral intake was resumed earlier (LA, 2.6 days; OA, 5.1 days; P<0.05). Postoperative stay was shorter in LA (LA, 11.7 days; OA, 25.8 days; P<0.001). Postoperative wound infection was less frequent in LA (LA, 8.8%; OA, 43.6%; P=0.0022).
Conclusions: Laparoscopic appendectomy for perforated appendicitis has significant advantages over open appendectomy with respect to frequency of analgesic use, start of oral feeding, postoperative stay, and postoperative wound infection.
6116 Gynecology
Reactionary Hemorrhage in Gynecological Surgery
Mark Erian, FRCOG, FRANZCOG, Glenda McLaren, FRCOG, FRANZCOG
Royal Brisbane Women’s Hospital
Introduction: To assess the incidence of reactionary hemorrhage in contemporary gynecological surgery, vaginal hysterectomy, and laparoscopic hysterectomy. This is a retrospective audit in a major teaching tertiary referral center.
Methods: There were 424 vaginal and 211 laparoscopic hysterectomies performed. The number of patients returning to the operating theater within 24 hours following the initial surgery was recorded. Immediate resuscitation was achieved followed by exploration laparoscopy, laparotomy, or both of these. Complete homeostasis must be accomplished before closure of the wound(s).
Results: Each group included 3 patients. The incidence was 0.7% in the vaginal hysterectomy group and 1.42% in the laparoscopic hysterectomy group. No association was noted between the incidence of reactionary hemorrhage and the patient’s BMI, uterine size, or pathology, eg, fibroid, adenomyosis; however, 4 of the 6 patients (2 in each group) had extensive pelvic adhesions attached to the uterus. The mean duration of laparoscopic procedures was 52 minutes (range, 29 to 75). The mean duration of laparotomy procedures was 28 minutes (range, 25 to 80). On average, in-patient hospital stay was prolonged by 1.5 days following laparoscopic management and 3 days in the laparotomy group. The average estimated blood loss was 2.5 liters (range, 2 to 3), as per the combined assessment of the gynecological and anesthetic teams. Following blood transfusion, all patients were started on “double” oral iron tablets, and the hemoglobin level was more than 80g/L before discharge.
Conclusion: Despite meticulous surgical technique, one would expect a very small proportion of patients to suffer from reactionary hemorrhage in contemporary gynecological surgery. Timely intervention is vital.
6117 Gynecology
Minilaparoscopy Assisted Natural Orifice Surgery
Daniel A. Tsin, MD
The Mount Sinai School of Medicine
Introduction: Interest has revived in peritoneoscopy via natural orifice surgery. Several of the limitations of this type of surgery could be solved with the minilaparoscopy assisted natural orifice surgery (MANOS) approach. We are using MANOS in operative culdoscopy.
Methods: The technique of culdolaparoscopy entails the use of minilaparoscopy limited to 3-mm abdominal ports, together with a 12-mm or larger natural orifice site, in this case, a vaginal port. The entrance from the natural orifice site into the peritoneal cavity is visualized and aided with minilaparoscopy. These ports are multifunctional. The natural orifice and the abdominal sites are used for insufflations, visual purposes, and introduction of operative instruments. The natural orifice port is also used for specimen extraction. We have used this technique in appendectomies, cholecystectomies, myomectomies, oophorectomies, and salpingoophorectomies.
Results: We have used this procedure in 100 cases. In this series, we had only one case of postoperative fever after an ovarian cystectomy, which was diagnosed as drug-related fever.
6118 General Surgery
Role and Value of the Predictive Factors of Common Biliary Duct Lithiasis
in Preparation for Laparoscopic Cholecystectomy: Retrospective Study
Vincenzo Neri, MD, Antonio Ambrosi, MD, Tiziano Pio Valentino, MD
University of Foggia
Introduction: The aim of this study was to evaluate the clinical-instrumental predictive
factors of common biliary duct stones (CBDS). Their presence is an indication for endoscopic retrograde cholangiopancreatography with endoscopic sphincterotomy (ERCP/ES) before the laparoscopic cholecystectomy (LC).
Methods: From 1997 through 2005, 102 ERCP/ES were performed; 76 patients were examined from 1999 to 2005. Patients with acute biliary pancreatitis (48) were excluded because, in our opinion, in these cases, the ERCP/ES has a therapeutic role, regardless of the suspicion of CBDS. We present a retrospective study of 28 ERCP/ES before the LC with the suspicion of CBDS. The clinical, instrumental, and bio-humoral data were analyzed by univariate and multivariate statistical studies.
Results: The univariate analysis identified alkaline phosphatase (P<0.0001), gamma-gt
(P<0.0001), direct bilirubin (P<0.0001), and CBD dilatation on abdominal ultrasonography (USG) (P<0.0001) as predictors of CBDS. A multivariate analysis subsequently identified alkaline phosphatase (P<0.0001), gamma-gt (P<0.0001), and direct bilirubin (P<0.0001) as independent predictive factors of CBDS; on the contrary,dilatation of the CBD (P=0.0759) was not statistically significant.
Conclusion: The dilatation of the CBD, alone, is not statistically significant.
The concordance of cholestasis factors with the dilatation of the CBD is
statistically significant for the diagnosis of CBDS, and it indicates the need for ERCP/ES before LC; however, the ERCP/ES, as an invasive procedure, cannot be performed before LC, if only the dilatation of the CBD is present, and an increase in cholestasis factors is absent.
6119 General Surgery
Assessing Decision Making in Laparoscopic Surgery
Sudip K. Sarker, MD, PhD, Saif Rheman, Avril Chang
Academic Surgery, Royal Free Hospital, Imperial College London, UK
Introduction: Making correct decisions is pivotal in the delivery of safe, effective, surgical healthcare, as well as being an integral part of surgical competency and excellence. To date, no attempt has been made to assess how and why surgeons make decisions while operating. In the present study, we aimed to develop and validate an operative decision-making tool in laparoscopic surgery.
Methods: Three decision-making modules were developed on a desktop computer program for laparoscopic cholecystectomy: knowledge, technical skill, and dynamics. The modules were based on didactic knowledge, technical skill, and intraoperative dynamic decision making. The last 2 modules were based on answering questions watching recorded live operations. The questions were devised by 2 experienced surgeons with >14 years postgraduate surgical experience. Three groups with varying degrees of surgical experience were assessed: novice (medical students), intermediate (junior surgeons), and expert (senior surgeons). These groups were determined by the number of laparoscopic cholecystectomies performed and the number of years of operative surgical experience.
Results: Thirty-five subjects were assessed: 15 novices, 12 intermediates, and 8 experts. Mean time to perform the program was 32 minutes (range, 21 to 45). Construct validity between the individual groups using the Mann-Whitney test was significant, P<0.05.
Conclusions: Our computer-based decision-making assessment tool in laparoscopic surgery seems to have face, content, concurrent, and construct validities. Surgical decision making is a multifaceted process; by assessing how and why decisions are made effectively, focused surgical training may be achieved.
6120 General Surgery
Preoperative Upper Endoscopy is Useful Prior to Revisional Bariatric Surgery
Benjamin Clapp, MD, Sherman Yu, MD, Trey Sands, MD, Erik Wilson, MD,Terry Scarborough, MD
Introduction: We hypothesized that patients who have previously had bariatric surgery and are undergoing revision to laparoscopic Roux-en-y gastric bypass would have abnormal findings detected by upper endoscopy that could potentially influence patient management. The procedures being revised included vertical banded gastroplasties, laparoscopic adjustable gastric bands, nonadjustable gastric bands, and previous Roux-n-y gastric bypasses (open and laparoscopic).
Methods: We conducted a retrospective chart review of patients who previously had undergone one of the above mentioned bariatric surgeries. We preoperatively performed an upper endoscopy on all patients. The endoscopy reports were reviewed and the findings entered into a database.
Results: Eighty-five percent of 55 patients needing revisional bariatric surgery had an abnormal upper endoscopy. Eleven percent had a gastrogastric fistula. Gastritis and esophagitis were noted in 65% and 37%, respectively. Eleven percent of patients had band erosion, 2 from a nonadjustable band, and 5 from vertical banded gastroplasties. Sixty-five percent of our patients required medical treatment based on our findings.
Conclusions: Preoperative upper endoscopy provides valuable information prior to
revisional laparoscopic bariatric surgery. In addition to identifying patients that need preoperative medications, the preoperative upper endoscopy also provided valuable information regarding pouch size and anatomy. Preoperative upper endoscopy should be performed by the operating surgeon on every patient undergoing revisional bariatric surgery.
6121 Gynecology
Ectopic Pregnancy
M. Sadok, MD, F. Haiba, MD, H. Ouzaa, MD
Hopital Militaire d’Oran-service Maternité
Introduction: Ectopic pregnancy is the development of fertilized ovum outside the uterine cavity. The frequency of ectopic pregnancy compared with the frequency of intrauterine pregnancy has been estimated to be between 1% and 3%. But the incidence is on the rise. We sought to determine the number of ectopic pregnancies managed at the Military Hospital of Oran over a 6-year period.
Methods: From January 2000 to December 2005, a study was conducted of ectopic pregnancies at the Military Hospital of Oran. We reviewed and analyzed the incidence, presentation on admission, and history of patients with ectopic pregnancy. The investigation included a pregnancy test, culdocentesis, transvaginal ultrasound, and laparoscopy.
Results: The total number of deliveries during the study period was 5000. The incidence of ectopic pregnancy was 1 in 100 normal intrauterine pregnancies.The 50 patients who had an ectopic pregnancy were included in the study.
Conclusion: The incidence of ectopic pregnancy at the Military Hospital of Oran over a 6-year period was 1 in 100 normal intrauterine pregnancies.
6122 General Surgery
Patient Recall and Comprehension after Laparoscopic Appendectomy
Benjamin Clapp, MD, Melba Jarmillo, BS, Luis Macias, MD, Valeria Vigil, MD,
Marcia Plett, PA-C, Cuatemoc Gallardo, MD, Andrew Kassir, MD
Introduction: The purpose of this study was to determine patient recall and comprehension after laparoscopic appendectomy in an underserved population.
Laparoscopic surgery can lead to diagnostic uncertainty secondary to poor recall and variable port placement.
Methods: After IRB approval, we identified a cohort of patients who underwent laparoscopic appendectomy from 2000 to 2004 at a single institution. We then attempted to contact the patients to conduct a 16-question telephone survey, which determined whether the patient spoke English or Spanish as a primary language, ethnicity, educational level, and questions about recall of perioperative events and diagnoses. If we could not reach the patient, we tried to call back on 3 different occasions.
Results: Between 2000 and 2004, 186 patients underwent laparoscopic appendectomy. Of these, 65% were Hispanic. We found that only 17% of these patients returned for a postoperative visit. Only 19.3% could be contacted by phone. Forty-seven percent of the patients contacted by phone spoke Spanish exclusively. Overall, 89% of patients contacted knew what operation they had and gave their correct diagnosis.
Conclusions: The low percentage of patients available to follow-up makes this study statistically insignificant. However, we believe that fact in itself is important. In Southwestern states, we see a large migrant population. This highlights the need to communicate effectively with patients at the time of laparoscopic surgery to avoid in the future the diagnostic uncertainty associated with laparoscopic incisions.
6123 General Surgery
K-ras Mutation as a Prognostic Factor in Colorectal Cancer Procedures: Laparoscopic vs. Laparotomic Approach
L. Sákra, MD, M. Sácha, MD, M. Rajman, MD
Surgical Department, General Hospital Pardubice, Czech Republic
Introduction: Colorectal carcinoma is a serious problem in the Czech Republic, and its incidence is on the rise. According to some statistical analyses, the Czech Republic has the highest incidence of colorectal carcinoma of developed countries worldwide. Therefore, it is advisable to incorporate new modalities into examination and therapeutic algorithms that will lead to early diagnosis or to a change in the existing therapeutic procedures.
Method: The main objective of this project was to identify K-ras mutations in colorectal tumors, to detect tumor cells with the K-ras mutation in the peripheral blood, to detect the K-ras mutation in liver metastases, and to verify the hypothesis claiming that tumors with the K-ras mutation have a worse prognosis and often metastasize, mainly to the liver. The outcomes of laparotomic versus laparoscopic procedures were analyzed.
Results: This project has been ongoing since June 2004. Seventy-five patients have met the defined parameters and have been included in the study to date.
Conclusion: The laparoscopic approach was monitored by the detection of the spread of tumor cells with K-ras mutation in the blood. This approach gives the same results as the results with laparotomic procedures.
6125 Gynecology
Complications from Hysterectomy
M. Sadok, MD, F. Haiba, MD, H. Ouzaa, MD
Department of Gynecology-Obstetrics, Oran Hôpital Militaire
Introduction: Hysterectomy is one of the most common major gynecological surgical procedures performed. Our objective was to determine the operative and postoperative complications of this procedure.
Methods: This study was conducted in the gynecology and obstetric service of Oran University Hospital Center from January 2000 to December 2005. Indications, complications, and mortality associated with hysterectomy were assessed.
Results: The number of hysterectomies performed in 6 years at our unit was 300. Major indications for hysterectomies were dysfunctional uterine bleeding (60%) and fibroid uterus, (35%) followed by prolapse (5%). Complications developed in 10% of these. The frequency of complications was related to the indication for hysterectomy, age, parity, and history of associated serious illness. It was found that the frequency of complications in fibroid uterus was higher (8%) than that for dysfunctional uterine bleeding (DUB) (2%). No operative deaths occurred.
Conclusion: We have a fairly high frequency of complications associated with hysterectomy. To reduce these complications, proper selection, preoperative preparation, and less invasive alternative treatment for the commonest indications of hysterectomy (ie, fibroids and DUB), for example various methods of endometrial ablation or resections, can be used.
6127 Gynecology
Moving Forward with Breast Endoscopy: From Diagnostic to Interventional Ductoscopy
Volker R. Jacobs, MD, PhD, MBA, Uta Euler, MD, PhD, Susanne Grunwald, MD, PhD,
Ralf Ohlinger, MD, PhD, Thorsten Fischer, MD, PhD, Marion Kiechle, MD, PhD,Stefan Paepke, MD, PhD
Frauenklinik (OB/GYN), Technical University, Munich, Germany Ernst-Moritz-Arndt-University, Greifswald, Germany
Introduction: Endoscopy of the breast, called ductoscopy, can give additional direct visual information about intraductal breast lesions that cannot be seen with conventional visual diagnostics like sonography, mammography, MRI, or galactography. After development and increasing application of diagnostic ductoscopy in Germany, research interest is shifting to interventional ductoscopy. We describe the evolution of interventional techniques and the use of newly developed devices for interventional ductoscopy.
Methods: In cooperation with PolyDiagnost, Pfaffenhofen, and Storz, Tuttlingen, all German, a variety of different instruments and techniques were developed and evaluated for clinical application. These were the vision-guided ductal lavage, a technique for acquisition of nipple aspirate fluid (NAF), vision-guided brush cytology of suspicious lesions with a 0.38-mm brush, removal of intraductal lesions with a 0.38-mm Titanium basket, a 0.8-mm vision-guided biopsy forceps, alternative visualization of breast ducts with addition of auto fluorescent light as well as use of 0.40-mm thin metal wires through the working channel for marking of intraductal findings or controlled retrieval of breast duct target lesions.
Results: The use of all miniature instruments is simple, safe, and effective. In our series, we have had no intra- or postoperative complications so far. Due to reusability of most instruments after appropriate sterilization according to instrument handling protocols, the instrument costs can be reduced in contrast to costs of disposable instruments. Interventional ductoscopy enhances diagnostic ductoscopy to a comprehensive and independent technique. Until establishment as a new standard, interventional ductoscopy remains experimental and should be further evaluated in multicenter trials for operative safety and equivalence to existing diagnostic and operative standards.
Conclusions: Interventional ductoscopy follows the principle of least minimal invasiveness and opens a variety of new options. With these new technical options, interventional ductoscopy seems to advance to become a potential one-stop screening method as well as a substitute for conventional procedures like ductectomy.
6128 Gynecology
A Comparative Study of Hysteroscopic Sterilization Performed In-office Versus a Hospital Operating Room
Mark Nichols, MD, James Carter, MD, Donald Fylstra, MD, and the Essure® System U.S. Post-Approval Study Group
Introduction: We compared hysteroscopic female sterilization procedures performed in-office versus a hospital operating room (OR) among newly trained physicians.
Methods: Subjects were a subset of a cohort enrolled in an FDA-mandated postapproval study. Both demographic and procedural differences between the groups were examined. For variables that were not normally distributed, the Mann Whitney-U statistic was used to determine whether significant differences existed. Normally distributed variables were evaluated by an independent samples t test or chi-square test, as appropriate.
Results: Inclusion criteria were met by 320 women enrolled in the study. In an OR, 252 procedures were performed, and 68 were performed in-office. No significant difference existed with regard to scope-in and scope-out time, with an average of 17 minutes in the OR and 15 minutes in-office. No significant difference existed in bilateral placement rates between the settings with a success rate of 88% in the OR and 91% in-office. The incidence of minor adverse events was comparable, with 2% of cases involving a minor adverse event in the OR and 1% in-office. Receipt of NSAIDs before the procedure was significantly related to successful bilateral placement. Among cases with successful bilateral placement, only 18% failed to receive NSAIDs before the procedure, whereas 33% of unsuccessful bilateral placements involved no NSAIDs (P=0.03).
Conclusion: No clear advantage exists to performing hysteroscopic sterilization in a hospital operating room. Hysteroscopic sterilization can be performed safely and efficiently in an office setting.
6129 General Surgery
Chronic Inguinal Pain After Laparoscopic Inguinal Hernia Repair: The Role of Tack and Mesh Removal
Jeffrey D. Sedlack, MD, Jonathan A. Laryea, MD
Department of Surgery, Waterbury Hospital, Waterbury, CT
Introduction: Chronic inguinal pain occurs as a postoperative complication in up to 8% of hernia repairs. Inguinal pain after laparoscopic hernia repair will typically resolve with time and conservative management. The question arises as to the treatment of patients with significant, ongoing pain that does not resolve over time.
Methods: Four patients have come under our care in the past year with severe, postoperative inguinodynia after TAPP laparoscopic inguinal hernia repairs with helical tack fixation of polypropylene mesh. All patients reported inguinal pain that continued despite maximal conservative therapy, including physical therapy, wound massage, ilioinguinal blocks, COX-2 inhibitors, and Neurontin. All patients were explored through transverse inguinal incisions. Implanted mesh and all tacks were identified and removed in all patients. Tack impingement of intramuscular segments of iliohypogastric nerves were identified in all cases. Neurolysis of the affected nerves was performed in all patients. In all of the patients, more than 10 fixation tacks were used, and tacks were placed lateral and superior to the inguinal ring.
Results: All patients experienced “significant” to “complete” permanent (>6 month) pain relief.
Conclusion: Removal of mesh and tacks and neurolysis of affected nerves is of benefit in the treatment of refractory inguinal pain after laparoscopic inguinal hernia repair. Further, there is likely a benefit in minimizing tack use and avoiding the superior and lateral quadrant of the inguinal floor to minimize the risk of injury to an intramuscular segment of the iliohypogastric nerve.
6130 General Surgery
The Impact of Routine Use of Preoperative ERCP in Gallstone Pancreatitis
Jonathan Laryea, MD, Jeffrey Sedlack, MD
Introduction: Despite over a decade of experience, the use of preoperative ERCP for the treatment of gallstone pancreatitis remains controversial. The purpose of this study is to determine whether preoperative ERCP is necessary in all patients with gallstone pancreatitis.
Methods: Charts of 30 patients admitted to Waterbury Hospital with a diagnosis of gallstone pancreatitis between 1998 and 2000 were reviewed for demographic data, length of stay, laboratory values (lipase, bilirubin, amylase, alkaline phosphatase levels), and results of radiographic studies. These patients were divided into 2 groups based on whether they underwent preoperative ERCP (n=20) or not (n=10). Differences between the groups in length of stay, complications, and laboratory data were analyzed with the Student t test and Fisher's exact text where appropriate (significance = P<0.05).
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